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ARS Pharmaceuticals (SPRY) Posts Q4 Loss of $0.42/Share as Revenue Jumps 332% YoY to $28.1M

Earnings Per Share (GAAP)
$-0.42
estimate N/A
Revenue
$28.1M
estimate N/A

Loss in match with the previous quarter. ARS Pharmaceuticals Inc. (NASDAQ: SPRY) reported a loss of $0.42 per share for Q4 2025, matching the prior quarter’s loss of $0.42 per share but swinging from a profit of $0.51 per share in the year-ago period. The 182% year-over-year decline marks a dramatic reversal for the biotechnology company, which posted its first profitable quarter a year ago. The company recorded a net loss of $41.3 million for the quarter.

Revenue surges despite profitability pressure. Revenue reached $28.1 million, down 13.5% from the prior quarter’s $32.5 million but up 332% from $6.5 million in Q4 2024. The sequential decline follows a strong Q3 2025 that saw revenue peak at $32.5 million, suggesting potential volatility in commercial uptake. The company held its earnings call at 8:30 AM ET on March 9 to discuss the results. Trading volume reached 1.5 million shares as the stock traded at $9.12, well below its 52-week high of $18.90.

What to Watch: The Q1 2026 earnings report will reveal whether the sequential revenue decline represents a temporary pause or a structural slowdown in commercial momentum. Management’s guidance on the earnings call will be critical for assessing whether the company can return to profitability while scaling revenue.

This article was generated using AlphaStreet’s proprietary financial analysis technology and reviewed by our editorial team.

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