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BioNTech (BNTX) Posts Q4 Loss of $-1.25/Share as Revenue Falls 23.8% YoY to $907.4M

Earnings Per Share (adj.)
$-1.25
estimate N/A
Revenue
$907.4M
estimate N/A

Loss deepens sharply. BioNTech SE reported an adjusted loss of -$1.25 per share for Q4 2025, matching the prior quarter’s loss of $0.33 but swinging from a profit of $1.08 per share in Q4 2024. The biotech posted a net loss of $305 million for the quarter, reflecting the sharp year-over-year reversal as COVID-19 vaccine revenue continues to normalize.

Revenue slides 23.8%. Quarterly revenue of $907.4 million declined 23.8% from $1.19 billion in the year-ago quarter, though it matched the prior quarter’s $907.4 million. The year-over-year contraction underscores the ongoing headwinds facing the company’s core vaccine franchise as pandemic-era demand fades. Trading volume reached 1.03 million shares as the stock held steady at $101.50.

What to Watch: The company’s earnings call at 8:00 AM ET will be critical for guidance on its oncology pipeline and any updates on next-generation vaccine development that could offset the COVID revenue decline.

This article was generated using AlphaStreet’s proprietary financial analysis technology and reviewed by our editorial team.

The post BioNTech (BNTX) Posts Q4 Loss of $-1.25/Share as Revenue Falls 23.8% YoY to $907.4M first appeared on Alphastreet.

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